For Laboratory Research – Not for Human Consumption

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Nomad Clinical

  • MOTS-C
  • MOTS-C
MOTS-C - Image 1 MOTS-C - Image 2

MOTS-C

Price range: €46.00 through €90.00

MOTS-c is a highly unique peptide encoded inside mitochondrial DNA that acts like a cellular messenger to mimic the metabolic benefits of physical exercise. While animal testing indicates it significantly enhances fat burning, muscle recovery, and insulin responsiveness, it remains an experimental compound confined strictly to laboratory settings.

Size

In biochemical and longevity research, scientists study MOTS-c to explore its profound role as an exercise-mimetic and systemic metabolic regulator. In vitro and animal models demonstrate that under metabolic demand, the peptide translocates to the cell nucleus where it binds to specific promoters to regulate adaptive gene expression. Researchers focus on how this nuclear interaction helps maintain systemic energy homeostasis, enhance glucose clearance, and drive cell-autonomous adaptations to oxidative stress.

Current Areas of Investigation

  • AMPK activation via the folate-AICAR pathway

  • Glucose uptake and GLUT4 transporter translocation

  • Fatty acid oxidation and lipid utilization

  • Mitochondrial biogenesis and cellular adaptation

  • Exercise-mimetic signaling and skeletal muscle homeostasis

Research Focus

In Simple Terms Scientific Focus
Cell power communication Retrograde mitochondrial-nuclear signaling
Exercise-like response AMPK pathway activation and energy adaptation
Muscle sugar uptake GLUT4 translocation and glucose metabolism
Enhanced fat burning Fatty acid $\beta$-oxidation and carnitine shuttle regulation
Metabolic longevity Preservation of systemic metabolic flexibility

Technical Specifications

Appearance

Lyophilized white powder

Storage Requirements

Store desiccated at −20°C for long-term molecular stability.

Research Disclaimer

MOTS-c supplied by Nomad Clinical is intended exclusively for laboratory research purposes. It is not approved as a medicinal product or food supplement and is not intended for human or veterinary use. References to published scientific literature are provided for educational purposes to summarize current areas of research and should not be interpreted as claims regarding the safety, efficacy, or intended use of this product.

Attributes Value
Size

10, 40

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