Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28-amino acid neuroregulatory peptide originally isolated from the gastrointestinal tract. It belongs to the glucagon/secretin superfamily and functions broadly across the central nervous system, immune system, and cardiovascular systems. Researchers are highly interested in VIP due to its potent role as a signaling molecule that modulates smooth muscle relaxation, blood flow, and systemic inflammatory responses.

In laboratory models, scientists investigate VIP to better understand its interactions with specific G-protein coupled receptors (VPAC1 and VPAC2). These pathways are studied for their potential to regulate immune homeostasis, protect epithelial barriers, and suppress pro-inflammatory cytokine production, making VIP a key focus in research surrounding autoimmune diseases, neuroprotection, and respiratory biology.

Current Areas of Investigation

• Smooth muscle relaxation and vasodilation

• Gastrointestinal motility and barrier function

• Neuroprotection and circadian rhythm regulation

• Respiratory tissue homeostasis

• Macrophage and T-cell regulation

Research Focus

Technical Specifications

Appearance

Lyophilized white powder

Storage Requirements

Store desiccated at −20°C for long-term molecular stability.

Research Disclaimer

VIP supplied by Nomad Clinical is intended exclusively for laboratory research purposes. It is not approved as a medicinal product or food supplement and is not intended for human or veterinary use. References to published scientific literature are provided for educational purposes to summarize current areas of research and should not be interpreted as claims regarding the safety, efficacy, or intended use of this product.